BAY 1214784

Modify Date: 2024-01-03 02:29:42

BAY 1214784 Structure
BAY 1214784 structure
Common Name BAY 1214784
CAS Number 1631164-25-4 Molecular Weight 672.11
Density N/A Boiling Point N/A
Molecular Formula C29H26ClF4N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAY 1214784


BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids[1].

 Names

Name BAY 1214784

 BAY 1214784 Biological Activity

Description BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids[1].
Related Catalog
References

[1]. Panknin O, et al. Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal Women. J Med Chem. 2020;63(20):11854-11881

 Chemical & Physical Properties

Molecular Formula C29H26ClF4N3O5S2
Molecular Weight 672.11