Fmoc-D-Trp(Boc)-OH structure
|
Common Name | Fmoc-D-Trp(Boc)-OH | ||
|---|---|---|---|---|
| CAS Number | 163619-04-3 | Molecular Weight | 526.580 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C31H30N2O6 | Melting Point | 86 - 92ºC (Decomposes) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Fmoc-D-Trp(Boc)-OHFmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs). |
| Name | (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Melting Point | 86 - 92ºC (Decomposes) |
| Molecular Formula | C31H30N2O6 |
| Molecular Weight | 526.580 |
| Exact Mass | 526.210388 |
| PSA | 106.86000 |
| LogP | 7.05 |
| Index of Refraction | 1.632 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
Solid-phase synthesis of C-terminal azapeptides.
J. Pept. Sci. 21 , 387-91, (2015) The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated ... |
| 1-(tert-Butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan |
| Nalpha-Fmoc-N(in)-Boc-D-tryptophan |
| AmbotzFAA1339 |
| Fmoc-D-Trp(Boc) |
| N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-tryptophan |
| D-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- |
| Fmoc-D-Trp(Boc)-OH |
| N|A-Fmoc-N(in)-Boc-D-tryptophan |
| Fmoc-L-Trp(Boc)-OH |
| MFCD00153367 |
| (2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid |