R-Avanafil

Modify Date: 2025-09-10 17:11:42

R-Avanafil Structure
R-Avanafil structure
Common Name R-Avanafil
CAS Number 1638497-26-3 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C23H26ClN7O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of R-Avanafil


(R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC50: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction[1].

 Names

Name R-Avanafil

 R-Avanafil Biological Activity

Description (R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC50: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction[1].
Related Catalog
Target

5.2 nM (PDE5)[1].

References

[1]. Sakamoto T, et al. The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5460-5.  

 Chemical & Physical Properties

Molecular Formula C23H26ClN7O3
InChIKey WEAJZXNPAWBCOA-MRXNPFEDSA-N
SMILES COc1ccc(CNc2nc(N3CCCC3CO)ncc2C(=O)NCc2ncccn2)cc1Cl
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