Vorasidenib (AG-881)

Modify Date: 2024-01-08 12:05:04

Vorasidenib (AG-881) structure	Common Name	Vorasidenib (AG-881)
	CAS Number	1644545-52-7	Molecular Weight	414.74
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₃ClF₆N₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Vorasidenib (AG-881)

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor.

Name	AG881
Synonym	More Synonyms

Description	Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH) Research Areas >> Cancer
Target	IDH[1]
In Vitro	Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more effective option for patients with IDH1/2 mutated glioma[1].
References	[1]. Fujii T, et al. Targeting isocitrate dehydrogenase (IDH) in cancer. Discov Med. 2016 May;21(117):373-80.

Molecular Formula	C₁₄H₁₃ClF₆N₆
Molecular Weight	414.74
Storage condition	-20℃

Vorasidenib

DC Chemicals Limited
China
Product Name: Vorasidenib (AG881)
Price: $500.0/100mg $900.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: $208/10mM*1mLinDMSO

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