Ac-Lys-Val-Cit-PABC-MMAE
Modify Date: 2025-11-10 07:42:33
Ac-Lys-Val-Cit-PABC-MMAE structure
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Common Name | Ac-Lys-Val-Cit-PABC-MMAE | ||
|---|---|---|---|---|
| CAS Number | 1650569-89-3 | Molecular Weight | 1293.64 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C66H108N12O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ac-Lys-Val-Cit-PABC-MMAEAc-Lys-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1]. |
| Name | Ac-Lys-Val-Cit-PABC-MMAE |
|---|
| Description | Ac-Lys-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1]. |
|---|---|
| Related Catalog | |
| Target |
Auristatin |
| References |
[1]. Kleniman, et al. Engineered polypeptide conjugates. WO2015015448A2. |
| Molecular Formula | C66H108N12O14 |
|---|---|
| Molecular Weight | 1293.64 |
| InChIKey | KCGMOXVVJSQNOS-IZNBURIHSA-N |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)c1ccccc1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)C(CCCCN)NC(C)=O)C(C)C)cc1)C(C)C |