Asn-Pro-Val-PABC-MMAE TFA

Modify Date: 2025-08-25 12:21:46

Asn-Pro-Val-PABC-MMAE TFA Structure
Asn-Pro-Val-PABC-MMAE TFA structure
Common Name Asn-Pro-Val-PABC-MMAE TFA
CAS Number 2893871-67-3 Molecular Weight 1291.50
Density N/A Boiling Point N/A
Molecular Formula C63H97F3N10O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Asn-Pro-Val-PABC-MMAE TFA


Asn-Pro-Val-PABC-MMAE TFA (compound 8) is a potent ADC Linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Asn-Pro-Val-PABC-MMAE TFA

 Asn-Pro-Val-PABC-MMAE TFA Biological Activity

Description Asn-Pro-Val-PABC-MMAE TFA (compound 8) is a potent ADC Linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
References

[1]. Mohamed Amar IA, et al. Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate. Eur J Med Chem. 2022 Feb 5;229:114063.  

 Chemical & Physical Properties

Molecular Formula C63H97F3N10O15
Molecular Weight 1291.50
InChIKey YJEOYBSNSJPQHG-YVTMPSISSA-N
SMILES CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)c1ccccc1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(NC(=O)C2CCCN2C(=O)C(N)CC(N)=O)C(C)C)cc1)C(C)C.O=C(O)C(F)(F)F
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