NOS-IN-1
Modify Date: 2025-08-25 16:55:04
NOS-IN-1 structure
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Common Name | NOS-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 165383-72-2 | Molecular Weight | 172.225 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H16N2O2 | Melting Point | 181-182ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of NOS-IN-1NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively[1]. |
| Name | 2-Imino-4-methylpiperidine, Acetate |
|---|---|
| Synonym | More Synonyms |
| Description | NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: 0.1 μM (hiNOS), 1.1 μM (heNOS), and 0.2 μM (hnNOS)[1] |
| In Vivo | Following oral administration, NOS-IN-1 (compound 3; 10 mg/kg) decreases serum nitrite/nitrate levels in an in vivo rat endotoxin assay[1]. |
| References |
| Melting Point | 181-182ºC |
|---|---|
| Molecular Formula | C8H16N2O2 |
| Molecular Weight | 172.225 |
| Exact Mass | 172.121185 |
| PSA | 73.18000 |
| LogP | 1.50260 |
| HS Code | 2933399090 |
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| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 2-Pyridinamine, 3,4,5,6-tetrahydro-4-methyl-, acetate (1:1) |
| 4-Methylpiperidin-2-imine acetate (1:1) |
| acetic acid,4-methyl-2,3,4,5-tetrahydropyridin-6-amine |
| 4-Methyl-3,4,5,6-tetrahydro-2-pyridinamine acetate (1:1) |
| 2-Piperidinimine, 4-methyl-, acetate (1:1) |