YAP-TEAD-IN-1 TFA

Modify Date: 2024-01-07 17:48:21

YAP-TEAD-IN-1 TFA structure	Common Name	YAP-TEAD-IN-1 TFA
	CAS Number	1659305-79-9	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉₃H₁₄₄ClN₂₃O₂₁S_2.xC₂HF₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of YAP-TEAD-IN-1 TFA

YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM)[1].

Name	YAP-TEAD-IN-1 TFA

Description	YAP-TEAD-IN-1 TFA is a potent and competitive peptide inhibitor of YAP-TEAD interaction (IC50=25 nM). YAP-TEAD-IN-1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50-171) (Kd= 40 nM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> YAP
Target	IC50: 25 nM (YAP-TEAD interaction)[1]
In Vitro	YAP-TEAD-IN-1 (peptide 17)(2 μM) is against endogenous YAP binding to GST-TEAD(1209-426) in a GST pull-down assay, the Kd of His-YAP(1209-426) is determined to be 40 nM[1].
References	[1]. Zhang Z, et al. Structure-Based Design and Synthesis of Potent Cyclic Peptides Inhibiting the YAP-TEAD Protein-Protein Interaction.ACS Med Chem Lett. 2014 Jul 14;5(9):993-8.

Molecular Formula	C₉₃H₁₄₄ClN₂₃O₂₁S_2.xC₂HF₃O₂

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: YAP-TEAD-IN-1 TFA
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Purity: 98.0%
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YAP-TEAD-IN-1 TFA

Use of YAP-TEAD-IN-1 TFA

Names

YAP-TEAD-IN-1 TFA Biological Activity

Chemical & Physical Properties