4-Formamidoantipyrine

Modify Date: 2024-01-02 08:25:48

4-Formamidoantipyrine Structure
4-Formamidoantipyrine structure
Common Name 4-Formamidoantipyrine
CAS Number 1672-58-8 Molecular Weight 231.251
Density 1.2±0.1 g/cm3 Boiling Point 374.5±52.0 °C at 760 mmHg
Molecular Formula C12H13N3O2 Melting Point 189-192ºC
MSDS Chinese USA Flash Point 180.3±30.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-Formamidoantipyrine


4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1].

 Names

Name 4-formylaminoantipyrine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 374.5±52.0 °C at 760 mmHg
Melting Point 189-192ºC
Molecular Formula C12H13N3O2
Molecular Weight 231.251
Flash Point 180.3±30.7 °C
Exact Mass 231.100784
PSA 56.03000
LogP 0.41
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.609
Storage condition Refrigerator

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Hazard Codes Xn
Risk Phrases 20/22
RIDADR NONH for all modes of transport
HS Code 2933199090

 Customs

HS Code 2933199090
Summary 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles19

More Articles
High-performance liquid chromatographic assay for metamizol metabolites in rat plasma: application to pharmacokinetic studies.

J. Pharm. Biomed. Anal. 71 , 173-8, (2012)

In order to evaluate the pharmacokinetics of metamizol in the presence of morphine in arthritic rats, after subcutaneous administration of the drugs, an easy, rapid, sensitive and selective analytical...

Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis-B virus does not occur in rapid acetylators.

Eur. J. Clin. Pharmacol. 57(6-7) , 461-5, (2001)

We previously found that, compared with healthy subjects. asymptomatic hepatitis-B virus (HBV) carriers displaying slow acetylator phenotype demonstrate a significant prolongation of the elimination h...

Simple high-performance liquid chromatographic method for simultaneous determination of aminopyrine and its metabolites.

J. Chromatogr. A. 421(1) , 198-205, (1987)

 Synonyms

4-formylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide
N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide
N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)carboxamide
(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imidoformic acid
4-Formylaminoantipyrine
Methanimidic acid, (2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylformamide
4-Formamidoantipyrine
Formamide,N-antipyrinyl
N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)formamide
4-formyl-aminoantipyrin
Formamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-
4-Formylaminoantipyrine (N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide
4-formaminoantipyrine
N-Formyl-4-aminoantipyrine
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