RS 39604 hydrochloride
Modify Date: 2024-01-15 15:22:50
RS 39604 hydrochloride structure
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Common Name | RS 39604 hydrochloride | ||
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| CAS Number | 167710-87-4 | Molecular Weight | 590.55900 | |
| Density | N/A | Boiling Point | 746.9ºC at 760 mmHg | |
| Molecular Formula | C26H37Cl2N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 405.5ºC | |
Use of RS 39604 hydrochlorideRS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites[1]. |
| Name | N-[2-[4-[3-[4-amino-5-chloro-2-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide,hydrochloride |
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| Synonym | More Synonyms |
| Description | RS 39604 is a potent, selective, and orally active 5-HT4 receptor antagonist with a pKi of 9.1 in guinea pig striatal membranes. RS 39604 displays a low affinity (pKi<6.5) for 5-HT1A, 5-HT2C, 5-HT3, α1c, D1, D2, M1, M2, AT1, B1 and opioid mu receptors and moderate affinity for δ1, (pKi=6.8) and δ2 (pKi=7.8) sites[1]. |
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| Related Catalog | |
| Target |
5-HT4 Receptor:9.1 (pKi) |
| References |
| Boiling Point | 746.9ºC at 760 mmHg |
|---|---|
| Molecular Formula | C26H37Cl2N3O6S |
| Molecular Weight | 590.55900 |
| Flash Point | 405.5ºC |
| Exact Mass | 589.17800 |
| PSA | 128.57000 |
| LogP | 6.53530 |
| Vapour Pressure | 1.25E-22mmHg at 25°C |
| GNF-Pf-5475 |