α-Conotoxin EI

Modify Date: 2024-01-12 12:16:20

α-Conotoxin EI structure	Common Name	α-Conotoxin EI
	CAS Number	170663-33-9	Molecular Weight	2093.37000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₈₃H₁₂₅N₂₇O₂₇S₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of α-Conotoxin EI

α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors[1][2][3].

Name	α-Conotoxin EI
Synonym	More Synonyms

Description	α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors[1][2][3].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
Target	IC50: 187 nM (nicotinic acetylcholine α1β1γδ receptor)[3]
In Vitro	α-Conotoxin EI (10 µM) blocks muscle and ganglionic receptors, but less potent for the central nevous system receptor[3]. α-Conotoxin EI (10 µM) blocks the α1β1γδ receptors with a τon of 4.9 s, and blocks the α3β4 receptor with a τon of 11 s[3].
In Vivo	α-Conotoxin EI (intraperitoneal injection) into mice induces muscular weakness, followed by flaccid paralysis and ultimately death[1].

Molecular Formula	C₈₃H₁₂₅N₂₇O₂₇S₅
Molecular Weight	2093.37000
Exact Mass	2091.78000
PSA	1002.01000

ARG-ASP-HYP-CYS-CYS-TYR-HIS-PRO-THR-CYS-ASN-MET-SER-ASN-PRO-GLN-ILE-CYS-NH2

A-CONOTOXIN EL

ARG-ASP-HYP-CYS-CYS-TYR-HIS-PRO-THR-CYS-ASN-MET-SER-ASN-PRO-GLN-ILE-CYS

RDHYPCCYHPTCNMSNPQIC-NH2

H-ARG-ASP-HYP-CYS-CYS-TYR-HIS-PRO-THR-CYS-ASN-MET-SER-ASN-PRO-GLN-ILE-CYS-NH2

a-Conotoxin El,Conus ermineus

Nanjing Peptide Biotech Ltd
China
Product Name: α-Conotoxin EI
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Taiwan Oyi peptide Co. Ltd
China
Product Name: α-Conotoxin EI
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

Get all suppliers and price by the below link:

α-Conotoxin EI suppliers

α-Conotoxin EI price