Andrastin A

Modify Date: 2024-01-04 09:01:39

Andrastin A Structure
Andrastin A structure
Common Name Andrastin A
CAS Number 174232-42-9 Molecular Weight 486.59700
Density 1.19g/cm3 Boiling Point 560.3ºC at 760 mmHg
Molecular Formula C28H38O7 Melting Point N/A
MSDS N/A Flash Point 236.1ºC

 Use of Andrastin A


Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species[1][2].

 Names

Name Andrastin A

 Andrastin A Biological Activity

Description Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species[1][2].
Related Catalog
References

[1]. Nielsen KF, et al. Andrastins A-D, Penicillium roqueforti Metabolites consistently produced in blue-mold-ripened cheese. J Agric Food Chem. 2005 Apr 20;53(8):2908-13.  

[2]. Rojas-Aedo JF, et al. The Biosynthetic Gene Cluster for Andrastin A in Penicillium roqueforti. Front Microbiol. 2017 May 5;8:813.  

 Chemical & Physical Properties

Density 1.19g/cm3
Boiling Point 560.3ºC at 760 mmHg
Molecular Formula C28H38O7
Molecular Weight 486.59700
Flash Point 236.1ºC
Exact Mass 486.26200
PSA 103.81000
LogP 3.86940
Vapour Pressure 1.39E-12mmHg at 25°C
Index of Refraction 1.54
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