5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one

Modify Date: 2025-08-25 11:06:20

5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one structure	Common Name	5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one
	CAS Number	1750-45-4	Molecular Weight	185.565
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₇H₄ClNO₃	Melting Point	240-242ºC
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of 5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one

6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[1].

Name	6-Hydroxy Chlorzoxazone
Synonym	More Synonyms

Description	6-Hydroxy Chlorzoxazone is a metabolite of Chlorzoxazone (HY-B1462). Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Elbarbry F, et al. Studying the Inhibitory Effect of Quercetin and Thymoquinone on Human Cytochrome P450 Enzyme Activities. Pharmacogn Mag. 2018 Jan;13(Suppl 4):S895-S899.

Density	1.6±0.1 g/cm3
Melting Point	240-242ºC
Molecular Formula	C₇H₄ClNO₃
Molecular Weight	185.565
Exact Mass	184.987976
PSA	66.23000
LogP	1.59
Index of Refraction	1.651
InChIKey	AGLXDWOTVQZHIQ-UHFFFAOYSA-N
SMILES	O=c1[nH]c2cc(Cl)c(O)cc2o1
Storage condition	2-8°C
Water Solubility	methanol: soluble

MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DM5260000

CHEMICAL NAME :: 2-Benzoxazolinone, 5-chloro-6-hydroxy-

CAS REGISTRY NUMBER :: 1750-45-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H4-Cl-N-O3

MOLECULAR WEIGHT :: 185.57

WISWESSER LINE NOTATION :: T56 BMVOJ GQ HG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),340,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),340,1964

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	DM5260000
HS Code	2934999090

Precursor 1
CAS#:95-25-0 Chlorzoxazone
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one

2(3H)-Benzoxazolone, 5-chloro-6-hydroxy-

5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6-Hydroxychlorzoxazone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Use of 5-Chloro-6-hydroxy-1,3-benzoxazol-2(3H)-one

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MSDS

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HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.