3-Hydroxybakuchiol

Modify Date: 2024-01-16 17:23:20

3-Hydroxybakuchiol Structure
3-Hydroxybakuchiol structure
Common Name 3-Hydroxybakuchiol
CAS Number 178765-54-3 Molecular Weight 272.382
Density 1.0±0.1 g/cm3 Boiling Point 437.6±45.0 °C at 760 mmHg
Molecular Formula C18H24O2 Melting Point N/A
MSDS N/A Flash Point 200.4±23.3 °C

 Use of 3-Hydroxybakuchiol


3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].

 Names

Name 3-Hydroxybakuchiol
Synonym More Synonyms

 3-Hydroxybakuchiol Biological Activity

Description 3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].
Related Catalog
References

[1]. Jaña F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64.  

[2]. Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 437.6±45.0 °C at 760 mmHg
Molecular Formula C18H24O2
Molecular Weight 272.382
Flash Point 200.4±23.3 °C
Exact Mass 272.177643
PSA 40.46000
LogP 5.95
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.574

 Safety Information

Hazard Codes Xi

 Synonyms

4-[(1E,3S)-3,7-Dimethyl-3-vinyl-1,6-octadien-1-yl]-1,2-benzenediol
1,2-Benzenediol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-
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