178765-54-3

178765-54-3 structure

Name: 3-Hydroxybakuchiol
Chemical Name: 3-Hydroxybakuchiol
CAS Number: 178765-54-3
Molecular Formula: C₁₈H₂₄O₂
Molecular Weight: 272.382
Catalog: Natural product Phenols
Create Date: 2016-02-02 09:52:14
Modify Date: 2024-01-16 17:23:20
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].

Name	3-Hydroxybakuchiol
Synonyms	4-[(1E,3S)-3,7-Dimethyl-3-vinyl-1,6-octadien-1-yl]-1,2-benzenediol 1,2-Benzenediol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-

Description	3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Jaña F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64. [2]. Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535.

Hazard Codes	Xi