TAMRA-PEG3-Azide

Modify Date: 2024-01-11 20:24:39

TAMRA-PEG3-Azide Structure
TAMRA-PEG3-Azide structure
Common Name TAMRA-PEG3-Azide
CAS Number 1228100-59-1 Molecular Weight 646.733
Density N/A Boiling Point N/A
Molecular Formula C33H38N6O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAMRA-PEG3-Azide


TAMRA-PEG3-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TAMRA-PEG3-Azide
Synonym More Synonyms

 TAMRA-PEG3-Azide Biological Activity

Description TAMRA-PEG3-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C33H38N6O7
Molecular Weight 646.733
Exact Mass 646.311523

 Synonyms

2-[6-(Dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]benzoate - N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)acetamide (1:1)
MFCD28334528
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