MT-031 structure
|
Common Name | MT-031 | ||
---|---|---|---|---|
CAS Number | 1802158-63-9 | Molecular Weight | 274.364 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C16H22N2O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of MT-031A potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo; inhibits H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells, and antagonizes scopolamine-induced memory and cognitive impairments in mice; upregulates mRNA expression levels of Bcl-2, the neurotrophic factors and the anti-inflammatory cytokine, Ntrk, and down-regulates the mRNA expression levels of IL-6 in scopolamine-induced mice. |
Name | MT-031 |
---|
Description | A potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo; inhibits H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells, and antagonizes scopolamine-induced memory and cognitive impairments in mice; upregulates mRNA expression levels of Bcl-2, the neurotrophic factors and the anti-inflammatory cytokine, Ntrk, and down-regulates the mRNA expression levels of IL-6 in scopolamine-induced mice. |
---|---|
References | References 1. Liu W, et al. Neuropharmacology. 2017 Feb;113(Pt A):445-456. 2. Liu W, et al. Neuropharmacology. 2016 Oct;109:376-385. View Related Products by Target Monoamine Oxidase (MAO) |
Molecular Formula | C16H22N2O2 |
---|---|
Molecular Weight | 274.364 |