L-Phenylalanine-13C6

Modify Date: 2024-01-11 18:46:58

L-Phenylalanine-13C6 Structure
L-Phenylalanine-13C6 structure
Common Name L-Phenylalanine-13C6
CAS Number 180268-82-0 Molecular Weight 171.15
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C313C6H11NO2 Melting Point 239-242° C
MSDS USA Flash Point N/A

 Use of L-Phenylalanine-13C6


L-Phenylalanine-13C6 ((S)-2-Amino-3-phenylpropionic acid-13C6) is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

 Names

Name L-Phenylalanine-¹³C6
Synonym More Synonyms

 L-Phenylalanine-13C6 Biological Activity

Description L-Phenylalanine-13C6 ((S)-2-Amino-3-phenylpropionic acid-13C6) is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Melting Point 239-242° C
Molecular Formula C313C6H11NO2
Molecular Weight 171.15
Exact Mass 171.099106
Index of Refraction 1.576

 Synonyms

L-(1,2,3,4,5,6-13C6)Phenylalanine
L-PHENYL-13C6-ALANINE
L-Phenylalanine-1,2,3,4,5,6-13C6
(2S)-2-Amino-3-phenylpropanoic Acid-13C6
MFCD00144663