AAK1-IN-2

Modify Date: 2025-08-26 13:27:11

AAK1-IN-2 Structure
AAK1-IN-2 structure
Common Name AAK1-IN-2
CAS Number 1802703-21-4 Molecular Weight 316.40
Density N/A Boiling Point N/A
Molecular Formula C20H20N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AAK1-IN-2


AAK1-IN-2 (compound (S)-31) is a potent, selective and brain-penetrant inhibitor of Adaptor Protein 2-Associated Kinase 1 (AAK1), with an IC50 of 5.8 nM. AAK1-IN-2 can be used for the research of neuropathic pain[1].

 Names

Name AAK1-IN-2

 AAK1-IN-2 Biological Activity

Description AAK1-IN-2 (compound (S)-31) is a potent, selective and brain-penetrant inhibitor of Adaptor Protein 2-Associated Kinase 1 (AAK1), with an IC50 of 5.8 nM. AAK1-IN-2 can be used for the research of neuropathic pain[1].
Related Catalog
Target

Adaptor Protein 2-Associated Kinase 1 (AAK1)[1]

References

[1]. Hartz RA, et, al. Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors. J Med Chem. 2022 Mar 10;65(5):4121-4155.

 Chemical & Physical Properties

Molecular Formula C20H20N4
Molecular Weight 316.40
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