USP8-IN-2

Modify Date: 2025-08-29 09:29:17

USP8-IN-2 Structure
USP8-IN-2 structure
Common Name USP8-IN-2
CAS Number 2477651-11-7 Molecular Weight 444.90
Density N/A Boiling Point N/A
Molecular Formula C19H20ClF3N4OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of USP8-IN-2


USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].

 Names

Name USP8-IN-2

 USP8-IN-2 Biological Activity

Description USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively[1].
Related Catalog
Target

USP8:6.0 μM (IC50)

References

[1]. Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.

 Chemical & Physical Properties

Molecular Formula C19H20ClF3N4OS
Molecular Weight 444.90
InChIKey XKLBIJSKEVHKCM-UHFFFAOYSA-N
SMILES COc1ccc(Cl)cc1NC(=S)NC1CCN(c2cccc(C(F)(F)F)n2)CC1
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