LG 100754
Modify Date: 2024-01-05 08:52:45
LG 100754 structure
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Common Name | LG 100754 | ||
|---|---|---|---|---|
| CAS Number | 180713-37-5 | Molecular Weight | 396.56200 | |
| Density | 1.003g/cm3 | Boiling Point | 549.4ºC at 760 mmHg | |
| Molecular Formula | C26H36O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 178.5ºC | |
Use of LG 100754LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR[1]. |
| Name | (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-6,7-dihydronaphthalen-2-yl)octa-2,4,6-trienoic acid |
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| Synonym | More Synonyms |
| Description | LG100754 (UVI 2112) is a RXR dimers modulater. LG100754 acts as a RXR:RXR homodimer antagonist, but functions as a agonist towards RXR:PPARα and RXR:PPARγ heterodimers. LG100754 is an insulin sensitizer that functions through RXR[1]. |
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| Related Catalog | |
| Target |
PPARα PPARγ |
| In Vitro | LG100754 is a selective activator of endogenous RXR heterodimers[1]. LG100754 can also improve TNFα-mediated insulin resistance in mature adipocytes[1]. LG100754 acts as a bona fide activator of endogenous RXR:PPARγ heterodimers and regulator of insulin-dependent signaling pathways[1]. |
| In Vivo | LG100754 (100 mg/kg) completely blocks the increase in glucose levels, suggesting that LG100754 can improve insulin resistance in vivo[1]. |
| References |
| Density | 1.003g/cm3 |
|---|---|
| Boiling Point | 549.4ºC at 760 mmHg |
| Molecular Formula | C26H36O3 |
| Molecular Weight | 396.56200 |
| Flash Point | 178.5ºC |
| Exact Mass | 396.26600 |
| PSA | 46.53000 |
| LogP | 6.81480 |
| Vapour Pressure | 6.63E-13mmHg at 25°C |
| Index of Refraction | 1.526 |
| RIDADR | NONH for all modes of transport |
|---|
| cd 3159 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: LG 100754
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: LG100754
- Price: $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: LG100754
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: (2E,4E,6Z)-3-Methyl-7-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-propoxy-3-naphthalenyl)-2,4,6-octatrienoicacid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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