ND-336

Modify Date: 2024-01-05 23:45:27

ND-336 Structure
ND-336 structure
Common Name ND-336
CAS Number 1807453-83-3 Molecular Weight 371.902
Density N/A Boiling Point N/A
Molecular Formula C16H17NO3S2•HCl Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ND-336


A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively; has minimal effect on other MMPs; accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition.

 Names

Name 1-(4-{4-[(2-Thiiranylmethyl)sulfonyl]phenoxy}phenyl)methanamine hydrochloride (1:1)
Synonym More Synonyms

 ND-336 Biological Activity

Description A selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively; has minimal effect on other MMPs; accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition.
References References 1. Gao M, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15226-31. View Related Products by Target Matrix Metalloproteinase (MMP)

 Chemical & Physical Properties

Molecular Formula C16H17NO3S2•HCl
Molecular Weight 371.902
Exact Mass 371.041656
Storage condition 2-8°C

 Synonyms

1-(4-{4-[(2-Thiiranylmethyl)sulfonyl]phenoxy}phenyl)methanamine hydrochloride (1:1)
Benzenemethanamine, 4-[4-[(thiiranylmethyl)sulfonyl]phenoxy]-, hydrochloride (1:1)
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