Acid-PEG3-mono-methyl ester

Modify Date: 2024-01-10 08:40:18

Acid-PEG3-mono-methyl ester Structure
Acid-PEG3-mono-methyl ester structure
Common Name Acid-PEG3-mono-methyl ester
CAS Number 1807505-26-5 Molecular Weight 264.272
Density 1.2±0.1 g/cm3 Boiling Point 396.7±32.0 °C at 760 mmHg
Molecular Formula C11H20O7 Melting Point N/A
MSDS N/A Flash Point 145.9±18.6 °C

 Use of Acid-PEG3-mono-methyl ester


Acid-PEG3-mono-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Acid-PEG3-mono-methyl ester
Synonym More Synonyms

 Acid-PEG3-mono-methyl ester Biological Activity

Description Acid-PEG3-mono-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 396.7±32.0 °C at 760 mmHg
Molecular Formula C11H20O7
Molecular Weight 264.272
Flash Point 145.9±18.6 °C
Exact Mass 264.120911
LogP -0.72
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.454

 Synonyms

3-Oxo-2,6,9,12-tetraoxapentadecan-15-oic acid
2,6,9,12-Tetraoxapentadecan-15-oic acid, 3-oxo-
MFCD28015772