EV-06
Modify Date: 2022-01-19 07:18:23
EV-06 structure
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Common Name | EV-06 | ||
|---|---|---|---|---|
| CAS Number | 1808266-58-1 | Molecular Weight | 327.934 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H26ClNO2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EV-06Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia. Alpha-LACE was designed to permeate biological membranes with the incorporation of the cationic choline head group. While lipoic acid does not permeate the cornea, the choline ester derivative of lipoic acid permeates the cornea, is hydrolyzed by corneal esterases and is transformed into the biologically active lipoic acid. LACE has been formulated into an ophthalmic solution to be applied twice daily as an eye-drop to treat presbyopia. |
| Name | -R-lipoic acid choline ester chloride |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C13H26ClNO2S2 |
|---|---|
| Molecular Weight | 327.934 |
| Exact Mass | 327.109344 |
| 2-({5-[(3R)-1,2-Dithiolan-3-yl]pentanoyl}oxy)-N,N,N-trimethylethanaminium chloride |
| Ethanaminium, 2-[[5-[(3R)-1,2-dithiolan-3-yl]-1-oxopentyl]oxy]-N,N,N-trimethyl-, chloride (1:1) |
| -R-lipoic acid choline ester chloride |