EV-06

• 常用名: EV-06
• 英文名: EV-06
• CAS号: 1808266-58-1
• 分子量: 327.934
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₃H₂₆ClNO₂S₂
• 熔点: N/A
• 闪点: N/A

EV-06用途

Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia. Alpha-LACE was designed to permeate biological membranes with the incorporation of the cationic choline head group. While lipoic acid does not permeate the cornea, the choline ester derivative of lipoic acid permeates the cornea, is hydrolyzed by corneal esterases and is transformed into the biologically active lipoic acid. LACE has been formulated into an ophthalmic solution to be applied twice daily as an eye-drop to treat presbyopia.

EV-06名称

• 英文名: -R-lipoic acid choline ester chloride

EV-06物理化学性质

• 分子式: C₁₃H₂₆ClNO₂S₂
• 分子量: 327.934
• 精确质量: 327.109344

EV-06英文别名

• 2-({5-[(3R)-1,2-Dithiolan-3-yl]pentanoyl}oxy)-N,N,N-trimethylethanaminium chloride
• Ethanaminium, 2-[[5-[(3R)-1,2-dithiolan-3-yl]-1-oxopentyl]oxy]-N,N,N-trimethyl-, chloride (1:1)
• -R-lipoic acid choline ester chloride