Remdesivir

Modify Date: 2024-01-03 18:50:24

Remdesivir Structure
Remdesivir structure
Common Name Remdesivir
CAS Number 1809249-37-3 Molecular Weight 602.576
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C27H35N6O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Remdesivir


Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.

 Names

Name remdesivir
Synonym More Synonyms

 Remdesivir Biological Activity

Description Remdesivir is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.
Related Catalog
Target

EC50: 30 nM (murine hepatitis virus, delayed brain tumor cell), 74 nM (SARS-CoV, HAE cell), 74 nM (MERS-CoV, HAE cell)[1]

In Vitro Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].
References

[1]. Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.

[2]. Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Molecular Formula C27H35N6O8P
Molecular Weight 602.576
Exact Mass 602.225403
LogP 2.10
Index of Refraction 1.652
Storage condition 2-8℃

 Synonyms

UNII:3QKI37EEHE
GS-5734
remdesivir
Top Suppliers:I want be here






Get all suppliers and price by the below link:

Remdesivir suppliers


Price: ¥7291/10 mM * 1 mL in DMSO

Reference only. check more Remdesivir price