BMS-1166
Modify Date: 2024-01-11 17:16:11
BMS-1166 structure
|
Common Name | BMS-1166 | ||
|---|---|---|---|---|
| CAS Number | 1818314-88-3 | Molecular Weight | 641.11 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H33ClN2O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS-1166BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. |
| Name | BMS-1166 |
|---|
| Description | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.4 nM (PD-1/PD-L1 interaction)[1]. |
| In Vitro | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay[1]. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1[2]. |
| References |
| Molecular Formula | C36H33ClN2O7 |
|---|---|
| Molecular Weight | 641.11 |
| Storage condition | 2-8℃ |