clausine E

Modify Date: 2025-08-26 00:36:44

clausine E Structure
clausine E structure
Common Name clausine E
CAS Number 182261-83-2 Molecular Weight 241.24
Density N/A Boiling Point N/A
Molecular Formula C14H11NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of clausine E


Clausine E, is a alkaloid which can be isolated from Clausena excavata, is a inhibitor of fat mass and obesity-associated protein (FTO) demethylase. Clausine E shows inhibitory activities against proliferation of synoviocytes and cancer cells.

 Names

Name clausine E
Synonym More Synonyms

 clausine E Biological Activity

Description Clausine E, is a alkaloid which can be isolated from Clausena excavata, is a inhibitor of fat mass and obesity-associated protein (FTO) demethylase. Clausine E shows inhibitory activities against proliferation of synoviocytes and cancer cells.
Related Catalog
References

[1]. Wang Y, Li J, Han X, et al. Identification of Clausine E as an inhibitor of fat mass and obesity-associated protein (FTO) demethylase activity. J Mol Recognit. 2019;32(10):e2800.  

[2]. Guo JM, Yu XM, Jiang B, et al. Zhongguo Zhong Yao Za Zhi. 2021;46(17):4438-4445.  

[3]. Liger F, Popowycz F, Besson T, Picot L, Galmarini CM, Joseph B. Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres. Bioorg Med Chem. 2007;15(16):5615-5619.  

 Chemical & Physical Properties

Molecular Formula C14H11NO3
Molecular Weight 241.24
Exact Mass 241.07400
PSA 62.32000
LogP 2.81330
InChIKey ZWPODTIRGFOENJ-UHFFFAOYSA-N
SMILES COC(=O)c1cc(O)c2[nH]c3ccccc3c2c1

 Safety Information

Hazard Codes Xi

 Synonyms

methyl 1-hydroxy-9H-carbazole-3-carboxylate
1-Hydroxy-9H-carbazole-3-carboxylic acid methyl ester
clauszoline I
clauszoline-I
clausine-E
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

clausine E suppliers

clausine E price

Related Compounds: More...
N-[[(E)-2-methyl-1-phenyl-but-2-enylidene]amino]-2,4-dinitro-aniline
7471-94-5
4-{(E)-[1-(3,5-Dichlorophenyl)-3-methyl-2,5-dioxo-4-imidazolidiny lidene]methyl}benzonitrile
509083-46-9
(Z,E)-2-<(4-methylphenyl)methylene>-3-(2-thienylmethylene)succinic anhydride
100047-13-0
methyl (E)-3-(thiophen-3-yl)acrylate
75754-85-7
methyl (E)-3-methoxybut-2-enoate
4525-28-4
Aegeline
456-12-2
Methyl (E)4.6-dichloro3-(2-oxo-1-phenyl-pyrrolidin-3-ylidenemethyl)-1H-indole-2-carboxylate
166974-21-6
2-[[(E)-1-hydroxy-3-oxo-prop-1-en-2-yl]carbamoyl]benzoic acid
81494-51-1
5-hydroxy-2-(4-hydroxyphenyl)-8,8-dimethyl-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxypyrano[2,3-h]chromen-4-one
113558-13-7
3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(4-methylpent-3-en-1-yl)carbamoyl]propanoic acid
2171589-54-9
2-({1-[(Benzyloxy)carbonyl]azetidin-3-yl}(methyl)amino)pyrimidine-5-carboxylic acid
2580197-53-9
4-(2-{[(Benzyloxy)carbonyl]amino}-1,1-difluoroethoxy)-3-methylbenzoic acid
2580241-31-0
2-[2-(3-{[(benzyloxy)carbonyl]amino}phenyl)-1H-imidazol-1-yl]acetic acid
2580228-23-3
3-(1-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylpropyl)benzoic acid
2580228-30-2
rac-methyl (1R,7S,8S,9R)-9-aminobicyclo[5.2.0]nonane-8-carboxylate
2580096-86-0
Tert-butyl octahydrocyclopenta[b][1,4]oxazine-6-carboxylate
2580216-08-4
Tert-butyl 2-ethyl-1,3-thiazinane-4-carboxylate
2580179-79-7
3-[(Benzyloxy)carbonyl]-2-(butan-2-yl)-1,3-thiazolidine-4-carboxylic acid
2580178-00-1
6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyrimidine-4-carboxylic acid
2580228-45-9