Azido-PEG4-(CH2)3-methyl ester

Modify Date: 2024-01-10 20:03:15

Azido-PEG4-(CH2)3-methyl ester Structure
Azido-PEG4-(CH2)3-methyl ester structure
Common Name Azido-PEG4-(CH2)3-methyl ester
CAS Number 1835759-71-1 Molecular Weight 319.35
Density N/A Boiling Point N/A
Molecular Formula C13H25N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG4-(CH2)3-methyl ester


Azido-PEG4-(CH2)3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG4-(CH2)3-methyl ester

 Azido-PEG4-(CH2)3-methyl ester Biological Activity

Description Azido-PEG4-(CH2)3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H25N3O6
Molecular Weight 319.35
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