ROS 234 dioxalate
Modify Date: 2024-01-05 11:56:42
ROS 234 dioxalate structure
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Common Name | ROS 234 dioxalate | ||
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| CAS Number | 184576-87-2 | Molecular Weight | 421.36100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H19N5O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ROS 234 dioxalateROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access[1][2]. |
| Name | ROS 234 dioxalate,N-[3-(1H-Imidazol-4-yl)propyl]-1H-benzimidazol-2-aminedioxalate |
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| Synonym | More Synonyms |
| Description | ROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access[1][2]. |
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| Related Catalog | |
| Target |
rat H3 receptor:8.90 (pKi) |
| In Vivo | ROS 234 centrally injected, significantly shortens pentobarbital narcosis[1]. |
| References |
| Molecular Formula | C17H19N5O8 |
|---|---|
| Molecular Weight | 421.36100 |
| Exact Mass | 421.12300 |
| PSA | 218.59000 |
| LogP | 0.71490 |
| ros 234 dioxalate |