RA-2 structure
|
Common Name | RA-2 | ||
---|---|---|---|---|
CAS Number | 1867107-62-7 | Molecular Weight | 414.356 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 590.5±50.0 °C at 760 mmHg | |
Molecular Formula | C22H16F2O6 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 310.9±30.1 °C |
Use of RA-2RA-2 is a negative-gating modulator of KCa2/3 channels with an IC50 of 17 nM. RA-2 inhibits bradykinin-induced endothelium-derived hyperpolarization (EDH)-type relaxation in U46619-precontracted rings. RA-2 can help to define the physiologic and pathomechanistic roles of KCa2/3 in the vasculature, central nervous system, and during inflammation[1]. |
Name | RA-2 |
---|---|
Synonym | More Synonyms |
Description | RA-2 is a negative-gating modulator of KCa2/3 channels with an IC50 of 17 nM. RA-2 inhibits bradykinin-induced endothelium-derived hyperpolarization (EDH)-type relaxation in U46619-precontracted rings. RA-2 can help to define the physiologic and pathomechanistic roles of KCa2/3 in the vasculature, central nervous system, and during inflammation[1]. |
---|---|
Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
---|---|
Boiling Point | 590.5±50.0 °C at 760 mmHg |
Molecular Formula | C22H16F2O6 |
Molecular Weight | 414.356 |
Flash Point | 310.9±30.1 °C |
Exact Mass | 414.091492 |
LogP | 5.91 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.620 |
1,3-Phenylenebis(methylene)bis(3-fluoro-4-hydroxybenzoate |
RA-2 |
1,3-Phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate) |
Benzoic acid, 3-fluoro-4-hydroxy-, 1,3-phenylenebis(methylene) ester |
1,1'-[1,3-Phenylenebis(methylene)]-3-fluoro-4-hydroxy-benzoic acid ester |