Name | RA-2 |
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Synonyms |
1,3-Phenylenebis(methylene)bis(3-fluoro-4-hydroxybenzoate
RA-2 1,3-Phenylenebis(methylene) bis(3-fluoro-4-hydroxybenzoate) Benzoic acid, 3-fluoro-4-hydroxy-, 1,3-phenylenebis(methylene) ester 1,1'-[1,3-Phenylenebis(methylene)]-3-fluoro-4-hydroxy-benzoic acid ester |
Description | RA-2 is a negative-gating modulator of KCa2/3 channels with an IC50 of 17 nM. RA-2 inhibits bradykinin-induced endothelium-derived hyperpolarization (EDH)-type relaxation in U46619-precontracted rings. RA-2 can help to define the physiologic and pathomechanistic roles of KCa2/3 in the vasculature, central nervous system, and during inflammation[1]. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 590.5±50.0 °C at 760 mmHg |
Molecular Formula | C22H16F2O6 |
Molecular Weight | 414.356 |
Flash Point | 310.9±30.1 °C |
Exact Mass | 414.091492 |
LogP | 5.91 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |
Index of Refraction | 1.620 |