5-Aminolevulinic acid-d2 hydrochloride

Modify Date: 2024-01-09 11:06:48

5-Aminolevulinic acid-d2 hydrochloride Structure
5-Aminolevulinic acid-d2 hydrochloride structure
Common Name 5-Aminolevulinic acid-d2 hydrochloride
CAS Number 187237-35-0 Molecular Weight 169.60
Density N/A Boiling Point N/A
Molecular Formula C5H8D2ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Aminolevulinic acid-d2 hydrochloride


5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).

 Names

Name 5-aminolevulinic-2,2-d2 acid hcl
Synonym More Synonyms

 5-Aminolevulinic acid-d2 hydrochloride Biological Activity

Description 5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.

[3]. Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.

 Chemical & Physical Properties

Molecular Formula C5H8D2ClNO3
Molecular Weight 169.60
Exact Mass 169.04700
PSA 80.39000
LogP 0.88130

 Synonyms

5-Aminolevulinic-2,2-D2 AcidHCI
5-Aminolevulinic-2,2-D2 AcidCI
2,2-dideutero-5-aminolevulinic acid hydrochloride
5-AMinolevulinic-d2 Acid HCl