AM-6494
Modify Date: 2025-08-26 19:51:27
AM-6494 structure
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Common Name | AM-6494 | ||
|---|---|---|---|---|
| CAS Number | 1874232-80-0 | Molecular Weight | 473.50 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H21F2N5O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AM-6494AM-6494 is a potent and orally active BACE1 (efficacious β-site amyloid precursor protein cleaving enzyme 1) inhibitor (IC50=0.4 nM) with in vivo selectivity over BACE2 (IC50=18.6 nM)[1]. |
| Name | AM-6494 |
|---|
| Description | AM-6494 is a potent and orally active BACE1 (efficacious β-site amyloid precursor protein cleaving enzyme 1) inhibitor (IC50=0.4 nM) with in vivo selectivity over BACE2 (IC50=18.6 nM)[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: (BACE1), 18.6 nM (BACE2)[1] |
| References |
| Molecular Formula | C22H21F2N5O3S |
|---|---|
| Molecular Weight | 473.50 |