AM 4668
Modify Date: 2024-01-07 09:05:23
AM 4668 structure
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Common Name | AM 4668 | ||
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| CAS Number | 1011531-27-3 | Molecular Weight | 488.48 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 633.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H19F3N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 336.9±34.3 °C | |
Use of AM 4668AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1]. |
| Name | (3S)-3-[4-({4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]-3-(1,2-oxazol-3-yl)propanoic acid |
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| Synonym | More Synonyms |
| Description | AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1]. |
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| Related Catalog | |
| Target |
EC50: 3.6 nM (GPR40, in A9 cells), 36 nM (GPR40, in CHO cells)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 633.4±65.0 °C at 760 mmHg |
| Molecular Formula | C24H19F3N2O4S |
| Molecular Weight | 488.48 |
| Flash Point | 336.9±34.3 °C |
| Exact Mass | 488.101776 |
| LogP | 5.27 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.583 |
| (3S)-3-[4-({4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]-3-(1,2-oxazol-3-yl)propanoic acid |
| 3-Isoxazolepropanoic acid, β-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl]-, (βS)- |