CX 614
Modify Date: 2024-01-14 15:56:48
CX 614 structure
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Common Name | CX 614 | ||
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| CAS Number | 191744-13-5 | Molecular Weight | 247.24700 | |
| Density | 1.45g/cm3 | Boiling Point | 473.8ºC at 760 mmHg | |
| Molecular Formula | C13H13NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 240.3ºC | |
Use of CX 614CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing the inactivation of responses to glutamate and automatically evokes excitatory postsynaptic currents in neuronal cultures. CX614 can be used in the study of psychiatric disorders such as depression[1][2]. |
| Name | cx614 |
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| Synonym | More Synonyms |
| Description | CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing the inactivation of responses to glutamate and automatically evokes excitatory postsynaptic currents in neuronal cultures. CX614 can be used in the study of psychiatric disorders such as depression[1][2]. |
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| Related Catalog | |
| In Vitro | CX614 (100 μM) 在 HEK293 细胞中，促进谷氨酸表观亲和力并增加谷氨酸诱发的内向电流，增加 3.5 和 10 mM 的谷氨酸反应峰值[1]。 |
| In Vivo | CX614 (1 or 10 mg/kg, i.p., twice a day) 明显增加 P5 小鼠海马和皮层的 BDNF mRNA，证实了 AMPA 受体的正向异生调节剂对海马 BDNF mRNA 水平的上调作用[2]。 |
| References |
| Density | 1.45g/cm3 |
|---|---|
| Boiling Point | 473.8ºC at 760 mmHg |
| Molecular Formula | C13H13NO4 |
| Molecular Weight | 247.24700 |
| Flash Point | 240.3ºC |
| Exact Mass | 247.08400 |
| PSA | 48.00000 |
| LogP | 1.35020 |
| Vapour Pressure | 3.82E-09mmHg at 25°C |
| Index of Refraction | 1.651 |
| Storage condition | 2-8°C |
| HS Code | 2934999090 |
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| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| CX 614 |
| BDP 37 |
| 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one |
| 6a,7,8,9-Tetrahydro-2H-[1,4]dioxino[2',3':4,5]benzo[1,2-e]pyrrolo[2,1-b][1,3]oxazin-11(3H)-one |
| LiD 37 |
| CX-614 |