SIB 1508Y maleate

Modify Date: 2025-08-27 16:23:13

Use of SIB 1508Y maleate

SIB-1508Y is an orally active and selective nAChR agonist. SIB-1508Y has the potential to study parkinsonism[1][2].

Name	3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine (2Z)-2-butenedioate (1:1)
Synonym	More Synonyms

Description	SIB-1508Y is an orally active and selective nAChR agonist. SIB-1508Y has the potential to study parkinsonism[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR Research Areas >> Neurological Disease
References	[1]. Cosford ND, et al. (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors. J Med Chem. 1996 Aug 16;39(17):3235-7. [2]. Schneider JS, et al. Effects of SIB-1508Y, a novel neuronal nicotinic acetylcholine receptor agonist, on motor behavior in parkinsonian monkeys. Mov Disord. 1998 Jul;13(4):637-42.

Description

SIB-1508Y is an orally active and selective nAChR agonist. SIB-1508Y has the potential to study parkinsonism[1][2].

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR

Signaling Pathways >> Neuronal Signaling >> nAChR

Research Areas >> Neurological Disease

References

3-Methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]pyridine (2Z)-2-butenedioate (1:1)

Pyridine, 3-methyl-5-[(2S)-1-methyl-2-pyrrolidinyl]-, (2Z)-2-butenedioate (1:1)