hACC2-IN-1
Modify Date: 2025-09-14 22:40:37
hACC2-IN-1 structure
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Common Name | hACC2-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 192323-14-1 | Molecular Weight | 432.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H32N2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of hACC2-IN-1hACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2). hACC2-IN-1 could be used for obesity research[1]. |
| Name | hACC2-IN-1 |
|---|
| Description | hACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2). hACC2-IN-1 could be used for obesity research[1]. |
|---|---|
| Related Catalog | |
| Target |
hACC2:2.5 μM (IC50) |
| In Vitro | ACC2 isoform, presents on the mitochondrial surface, inhibits carnitine palmitoyl transferase 1 (CPT-1) and converts acetyl-CoA into malonylCoA for de novo lipogenesis in the cytosol[1]. ACCs inhibition will change cellular substrate and favour lipid oxidation, thus preventing deleterious lipids from accumulating in oxidative tissue such as muscle, heart and liver[1]. hACC2-IN-1 shows good potency against the human ACC2 (hACC2) enzyme[1]. |
| References |
| Molecular Formula | C23H32N2O4S |
|---|---|
| Molecular Weight | 432.58 |
|
Name: Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell ass...
Source: ChEMBL
Target: Acetyl-CoA carboxylase 2
External Id: CHEMBL1820814
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