2'-Deoxyadenosine-5'-triphosphate

Modify Date: 2024-01-04 18:53:16

2'-Deoxyadenosine-5'-triphosphate Structure
2'-Deoxyadenosine-5'-triphosphate structure
Common Name 2'-Deoxyadenosine-5'-triphosphate
CAS Number 1927-31-7 Molecular Weight 535.145
Density 2.5±0.1 g/cm3 Boiling Point 913.3±75.0 °C at 760 mmHg
Molecular Formula C10H14N5Na2O12P3 Melting Point N/A
MSDS Chinese USA Flash Point 506.1±37.1 °C

 Use of 2'-Deoxyadenosine-5'-triphosphate


2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase[1].

 Names

Name dATP
Synonym More Synonyms

 2'-Deoxyadenosine-5'-triphosphate Biological Activity

Description 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase[1].
Related Catalog
References

[1]. P J Romaniuk, A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate. J Biol Chem. 1982 Jul 10;257(13):7684-8.

 Chemical & Physical Properties

Density 2.5±0.1 g/cm3
Boiling Point 913.3±75.0 °C at 760 mmHg
Molecular Formula C10H14N5Na2O12P3
Molecular Weight 535.145
Flash Point 506.1±37.1 °C
Exact Mass 534.964722
PSA 321.68000
LogP -4.93
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.874
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7358800
CHEMICAL NAME :
Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate)
CAS REGISTRY NUMBER :
1927-31-7
BEILSTEIN REFERENCE NO. :
0071964
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H16-N5-O12-P3
MOLECULAR WEIGHT :
491.22
WISWESSER LINE NOTATION :
T56 BN DN FN HNT&J IZ D- ET5OTJ B1OPQO&OPQO&OPQQO CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
33600 nmol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,2092,1982

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AU7358800
Packaging Group III

 Synthetic Route

~23%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Tetrahedron Letters, , vol. 27, # 46 p. 5641 - 5644

~89%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Bioscience, biotechnology, and biochemistry, , vol. 64, # 9 p. 1836 - 1841

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: U.S.Atomic Energy Comm., NYO-2055<1957>1,3,5

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: US2795580 , ;

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Journal of Biological Chemistry, , vol. 233, p. 163,165

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Nucleosides and Nucleotides, , vol. 18, # 4-5 p. 857 - 860

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 28, # 8 p. 776 - 792

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Biochimica et Biophysica Acta, , vol. 35, p. 405,409

~%

2'-Deoxyadenosine-5'-triphosphate Structure

2'-Deoxyadenosi...

CAS#:1927-31-7

Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 27, # 6-7 p. 872 - 875

 Articles32

More Articles
Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.

Biochim. Biophys. Acta 1824(4) , 679-91, (2012)

The ribosome inactivating proteins (RIPs) of type 1 are plant toxins that eliminate adenine base selectively from the single stranded loop of rRNA. We report six crystal structures, type 1 RIP from Mo...

Mechanism and fidelity of HIV reverse transcriptase.

J. Biol. Chem. 267 , 25988-25997, (1992)

We have examined the RNA-dependent and DNA-dependent polymerase and ribonuclease H catalytic activities of human immunodeficiency virus reverse transcriptase using rapid transient kinetic methods with...

Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation.

Biochemistry 31 , 4473-4479, (1992)

Steady-state and pre-steady-state kinetic constants were determined for reverse transcriptase catalyzed incorporation of nucleotides and nucleotide analogues into defined-sequence DNA primed-RNA templ...

 Synonyms

5'-DATP
DATP,LI
Disodium 2'-deoxy-5'-O-({[(phosphonooxy)phosphinato]oxy}phosphinato)adenosine
2'-Deoxy-ATP
deoxyribose adenosine triphosphate
Deoxyadenosine triphosphate
Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate)
EINECS 217-662-3
2'-Deoxyadenosine-5'-triphosphate disodium salt
2'-Datp
2'-DEOXYADENOSINE-5'-TRIPHOSHATE
DATP LI-SALT
2'-Deoxyadenosine 5'-(tetrahydrogen triphosphate)
deoxyadenosinetriphosphate
deoxy-atp
[32P]-2'-Deoxyadenosine triphosphate
dATP
Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), sodium salt (1:2)
2'-Deoxyadenosine-5'-triphosphate
deoxyadenosine-triphosphate
2'-Deoxyadenosine 5'-triphosphate
MFCD00672265
Top Suppliers:I want be here




Get all suppliers and price by the below link:

2'-Deoxyadenosine-5'-triphosphate suppliers


Price: ¥1544.4/250mg

Reference only. check more 2'-Deoxyadenosine-5'-triphosphate price