Adenosine triphosphate

Modify Date: 2025-08-20 17:39:25

Adenosine triphosphate structure	Common Name	Adenosine triphosphate
	CAS Number	56-65-5	Molecular Weight	507.181
	Density	2.6±0.1 g/cm3	Boiling Point	951.4±75.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₆N₅O₁₃P₃	Melting Point	187 - 190ºC (Decomposes)
	MSDS	N/A	Flash Point	529.2±37.1 °C

Use of Adenosine triphosphate

ATP is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells.

Name	atp
Synonym	More Synonyms

Description	ATP is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells.
Related Catalog	Natural Products >> Others Research Areas >> Neurological Disease
Target	Human Endogenous Metabolite
In Vitro	ATP (100-300 µM) inhibits the production of TNF-α by 32±8%, and at 300 µM, the attenuation of TNF-α production is 65±4% in LPS + PHA-stimulated whole blood. ATP (100, 300 µM) increases IL-10 levels by 48±5% (p=0.01) and 62±7%, respectively, in LPS + PHA-stimulated whole blood. ATP does not significantly alter the production of IL-6.
References	[1]. Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8.

Density	2.6±0.1 g/cm3
Boiling Point	951.4±75.0 °C at 760 mmHg
Melting Point	187 - 190ºC (Decomposes)
Molecular Formula	C₁₀H₁₆N₅O₁₃P₃
Molecular Weight	507.181
Flash Point	529.2±37.1 °C
Exact Mass	506.995758
PSA	308.56000
LogP	-4.18
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.904
InChIKey	ZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES	Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7416000

CHEMICAL NAME :: Adenosine 5'-(tetrahydrogen triphosphate)

CAS REGISTRY NUMBER :: 56-65-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H16-N5-O13-P3

MOLECULAR WEIGHT :: 507.22

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQO&OPQO&OPQQO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2780 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 2 umol/L

REFERENCE :: CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 27,61,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3124 No. of Facilities: 351 (estimated) No. of Industries: 1 No. of Occupations: 8 No. of Employees: 6576 (estimated) No. of Female Employees: 5259 (estimated)

Hazard Codes	Xi
Safety Phrases	S22-S24/25
WGK Germany	3

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