RG-101

Modify Date: 2025-08-25 19:56:54

RG-101 Structure
RG-101 structure
 Common Name RG-101
CAS Number 1929655-04-8 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RG-101


RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].

 Names

Name RG-101

 RG-101 Biological Activity

Description RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].
Related Catalog
In Vitro RG-101 is a mixed chemistry phosphorothioate oligonucleotide inhibitor of miR-122 that is linked to a multivalent N-acetylgalactosamine carbohydrate structure designed to enhance uptake of the oligonucleotide by hepatocytes through binding to the asialoglycoprotein receptor on hepatocytes[1].
References

[1]. Meike H van der Ree, et al. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial. Lancet. 2017 Feb 18;389(10070):709-717.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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Chemsrc provides RG-101(CAS#:1929655-04-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of RG-101 are included as well.>> amp version: RG-101

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