Biotin-PEG12-NHS ester

Modify Date: 2024-01-18 05:17:08

Biotin-PEG12-NHS ester Structure
Biotin-PEG12-NHS ester structure
Common Name Biotin-PEG12-NHS ester
CAS Number 1934296-88-4 Molecular Weight 941.09
Density N/A Boiling Point N/A
Molecular Formula C41H72N4O18S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG12-NHS ester


Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG12-NHS ester

 Biotin-PEG12-NHS ester Biological Activity

Description Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C41H72N4O18S
Molecular Weight 941.09