Prosaptide Tx14(A) TFA
Modify Date: 2025-09-20 17:59:49
Prosaptide Tx14(A) TFA structure
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Common Name | Prosaptide Tx14(A) TFA | ||
|---|---|---|---|---|
| CAS Number | 196391-82-9 | Molecular Weight | 1579.70 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C69H110N16O26 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Prosaptide Tx14(A) TFAProsaptide Tx14(A), a prosaposin-derived peptide, is a potent GPR37L1 and GPR37 agonist with EC50s of 5 and 7 nM, respectively. Prosaptide Tx14(A) increases both ERK1 and ERK2 phosphorylation in Schwann cells[1][2]. |
| Name | Prosaptide Tx14(A) |
|---|
| Description | Prosaptide Tx14(A), a prosaposin-derived peptide, is a potent GPR37L1 and GPR37 agonist with EC50s of 5 and 7 nM, respectively. Prosaptide Tx14(A) increases both ERK1 and ERK2 phosphorylation in Schwann cells[1][2]. |
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| Related Catalog | |
| In Vitro | Prosaptide Tx14(A) promotes the endocytosis of GPR37 and GPR37L1, bound to both receptors and activated signaling in a GPR37- and GPR37L1-dependent manner. Prosaptide Tx14(A) is the active fragment of the secreted neuroprotective and glioprotective factor prosaposin (also known as sulfated glycoprotein-1)[1]. |
| References |
| Molecular Formula | C69H110N16O26 |
|---|---|
| Molecular Weight | 1579.70 |
| InChIKey | SMUKRAODILXPSW-SRWCCNGVSA-N |
| SMILES | CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(NC(=O)C(C)NC(=O)C(CC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CC(=O)O)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(N)C(C)O)C(C)CC)C(C)O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)O |