1-Deoxysphinganine (m18:0)

Modify Date: 2024-01-14 04:34:06

1-Deoxysphinganine (m18:0) structure	Common Name	1-Deoxysphinganine (m18:0)
	CAS Number	196497-48-0	Molecular Weight	285.50800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₃₉NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 1-Deoxysphinganine (m18:0)

Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation[1].

Name	(2S,3R)-2-aminooctadecan-3-ol
Synonym	More Synonyms

Description	Spisulosine (ES-285) is an antiproliferative (antitumoral) compound of marine origin. Spisulosine inhibits the growth of the prostate PC-3 and LNCaP cells through intracellular ceramide accumulation and PKCζ activation[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> TGF-beta/Smad >> PKC
Target	PKCζ
References	[1]. Ana M Sánchez, et al. Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCzeta activation. Eur J Pharmacol. 2008 Apr 28;584(2-3):237-45.

Molecular Formula	C₁₈H₃₉NO
Molecular Weight	285.50800
Exact Mass	285.30300
PSA	46.25000
LogP	5.87610

Spisulosine

2S-amino-octadecan-3R-ol

1-deoxy-sphinganine

1-deoxysphinganine (0)

(2S,3R)-2-amino-3-hydroxyoctadecane

Spisulosine(2S,3R)-2-amino-3-hydroxy-octadecane ES-2851-deoxy SA1-deoxySa

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: spisulosine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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1-Deoxysphinganine (m18:0)

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1-Deoxysphinganine (m18:0) Biological Activity

Chemical & Physical Properties

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