JAK-IN-14

Modify Date: 2024-04-01 18:20:09

JAK-IN-14 Structure
JAK-IN-14 structure
Common Name JAK-IN-14
CAS Number 1973485-06-1 Molecular Weight 334.35
Density N/A Boiling Point N/A
Molecular Formula C19H15FN4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JAK-IN-14


JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of <5 μM. JAK-IN-14 is >8-fold more selective for JAK1 than JAK2 and JAK3 (Patent WO2016119700A1, compound 16)[1].

 Names

Name JAK-IN-14

 JAK-IN-14 Biological Activity

Description JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of <5 μM. JAK-IN-14 is >8-fold more selective for JAK1 than JAK2 and JAK3 (Patent WO2016119700A1, compound 16)[1].
Related Catalog
References

[1]. Jin Li, et al. Substituted imidazo [1, 2-a] pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof. WO2016119700A1.

 Chemical & Physical Properties

Molecular Formula C19H15FN4O
Molecular Weight 334.35
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