Z-FA-FMK

Modify Date: 2025-09-01 19:31:30

Z-FA-FMK structure	Common Name	Z-FA-FMK
	CAS Number	197855-65-5	Molecular Weight	386.417
	Density	1.2±0.1 g/cm3	Boiling Point	630.5±55.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₃FN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	335.1±31.5 °C

Use of Z-FA-FMK

Z-FA-FMK ((1S)-Z-FA-FMK; Compound 6) is a broad-spectrum halomethyl ketone inhibitor sgainst Coronavirus (SARS-CoV) main protease 3CL with a Ki of 25.7 μM[1].

Name	z-phe-dl-ala-fluoromethylketone
Synonym	More Synonyms

Description	Z-FA-FMK ((1S)-Z-FA-FMK; Compound 6) is a broad-spectrum halomethyl ketone inhibitor sgainst Coronavirus (SARS-CoV) main protease 3CL with a Ki of 25.7 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	Ki: 25.7 μM (SARS Protease 3CLpro)[1]
References	[1]. Usman Bacha, et al. Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chem Biol Drug Des. 2008 Jul;72(1):34-49.

Density	1.2±0.1 g/cm3
Boiling Point	630.5±55.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₃FN₂O₄
Molecular Weight	386.417
Flash Point	335.1±31.5 °C
Exact Mass	386.164185
PSA	84.50000
LogP	3.67
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.549
InChIKey	ASXVEBPEZMSPHB-PKHIMPSTSA-N
SMILES	CC(NC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)CF
Storage condition	-15°C

Name: Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
Source: NCGC
External Id: IP6K1-p1

Name: Compound was tested for inhibitory activity against cathepsin B
Source: ChEMBL
Target: Cathepsin B
External Id: CHEMBL657296

Name: Rate of cathepsin B inactivation in vitro in bovine spleen
Source: ChEMBL
Target: Cathepsin B
External Id: CHEMBL659002

Name: Compound was tested for inhibitory uM
Source: ChEMBL
Target: Calpain-1 catalytic subunit
External Id: CHEMBL658529

Name: Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans...
Source: NCGC
External Id: MTASE-p

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

Name: Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
Source: NCGC
External Id: NSD2-synergy-p-2C

Name: Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
Source: NCGC
External Id: NSD2-synergy-p-9B

Name: Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ...
Source: NCGC
External Id: s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

Name: Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli using DABCYL-KTS...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL5147543

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Z-FA-FMK
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.