197855-65-5

197855-65-5 structure

Name: Z-FA-FMK
Chemical Name: z-phe-dl-ala-fluoromethylketone
CAS Number: 197855-65-5
Molecular Formula: C₂₁H₂₃FN₂O₄
Molecular Weight: 386.417
Catalog: Biochemical Inhibitor Proteases Cysteine Protease Inhibitor
Create Date: 2017-08-18 15:45:49
Modify Date: 2026-07-01 11:58:29
Z-FA-FMK ((1S)-Z-FA-FMK; Compound 6) is a broad-spectrum halomethyl ketone inhibitor sgainst Coronavirus (SARS-CoV) main protease 3CL with a Ki of 25.7 μM[1].

Name	z-phe-dl-ala-fluoromethylketone
Synonyms	Inhibitor of cysteine proteases Nalpha-[(Benzyloxy)carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk z-fa-fmk Z-PHE-DL-ALA-FLUOROMETHYLKETONE Carbamic acid, N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)cbamate Nα-[(Benzyloxy)carbonyl]-N-(4-fluoro-3-oxo-2-butanyl)-L-phenylalaninamide Nalpha-[(Benzyloxy)carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide SS coronavirus,SS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus rlication,ZFAFMK Z-Phe-DL-Ala-FMK UNII:34O3P3306Z Nα-[(Benzyloxy)carbonyl]-N-(4-fluoro-3-oxo-2-butanyl)phenylalaninamide Carbamic acid, N-[2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-, phenylmethyl ester Cbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester Z-FA-FMK, 10 mM in DMSO

Description	Z-FA-FMK ((1S)-Z-FA-FMK; Compound 6) is a broad-spectrum halomethyl ketone inhibitor sgainst Coronavirus (SARS-CoV) main protease 3CL with a Ki of 25.7 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
Target	Ki: 25.7 μM (SARS Protease 3CLpro)[1]
References	[1]. Usman Bacha, et al. Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro). Chem Biol Drug Des. 2008 Jul;72(1):34-49.