Cholesterol myristate
Modify Date: 2024-01-02 23:31:07
Cholesterol myristate structure
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Common Name | Cholesterol myristate | ||
|---|---|---|---|---|
| CAS Number | 1989-52-2 | Molecular Weight | 597.00900 | |
| Density | 0.95 g/cm3 | Boiling Point | 630.7ºC at 760 mmHg | |
| Molecular Formula | C41H72O2 | Melting Point | 84 °C | |
| MSDS | N/A | Flash Point | 334.8ºC | |
Use of Cholesterol myristateCholesterol myristate is a natural steroid present in traditional Chinese medicine. |
| Name | cholesteryl myristate |
|---|---|
| Synonym | More Synonyms |
| Description | Cholesterol myristate is a natural steroid present in traditional Chinese medicine. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | Mesenchymal stem cells (MSCs) transfected by the Id1 promoter reporter construct, cholesterol myristate increases the activity of Id1 promoter. Cholesterol myristate inhibits the apoptosis of MSCs induced by serum-free. Cholesterol myristate increases the expression of Id1 and its target gene bcl-x/l in MSCs treated with serum-free. Moreover, noggin, a BMP antagonist, reduces the anti-apoptotic effects of cholesterol myristate[1]. Cholesterol myristate inhibits the apoptosis of PC12 cells induced in serum-free condition. Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition[1]. |
| Cell Assay | MSCs are cultured with or without serum in 96-well plates and treated with cholesterol myristate in various concentrations (0, 30 and 300 μg/mL) for 3 days. Each sample is repeated in five independent wells and is incubated for 72 h. After incubation, 20 μL MTT (5 mg/mL) is added and the culture is incubated for a further 4 h. The culture medium is discarded and replaced with 150 μL DMSO. The absorbance at 490nm is measured[1]. |
| References |
| Density | 0.95 g/cm3 |
|---|---|
| Boiling Point | 630.7ºC at 760 mmHg |
| Melting Point | 84 °C |
| Molecular Formula | C41H72O2 |
| Molecular Weight | 597.00900 |
| Flash Point | 334.8ºC |
| Exact Mass | 596.55300 |
| PSA | 26.30000 |
| LogP | 12.64070 |
| Vapour Pressure | 8.15E-16mmHg at 25°C |
| Index of Refraction | 1.506 |
| Storage condition | −20°C |
| Precursor 4 | |
|---|---|
| DownStream 0 | |
CAS#:57-88-5
CAS#:544-63-8
CAS#:112-64-1
CAS#:124-10-7| Cholesterol=tetradecanoate |
| CHOLESTERYL TETRADODEDECANOATE |
| EINECS 217-867-8 |
| Cholesteryl myristate |
| Cholest-5-en-3-yl myristate |
| Cholesterol Myristate |
| Cholestryl myristate |
| MFCD00014256 |
| Myristic Acid Cholesterol Ester |
| O-myristoyl-cholesterol |
| cholesteryl tetradecanoate |
| Cholestryl myristic acid |
| Myristinsaeure-cholesterylester |