D-erythro-Neopterin

Modify Date: 2024-01-03 18:46:19

D-erythro-Neopterin Structure
D-erythro-Neopterin structure
Common Name D-erythro-Neopterin
CAS Number 2009-64-5 Molecular Weight 253.215
Density 2.0±0.1 g/cm3 Boiling Point 697.7ºC at 760mmHg
Molecular Formula C9H11N5O4 Melting Point >232ºC (dec.)
MSDS Chinese USA Flash Point 375.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of D-erythro-Neopterin


D-(+)-Neopterin, a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.

 Names

Name d-(+)-neopterin
Synonym More Synonyms

 D-erythro-Neopterin Biological Activity

Description D-(+)-Neopterin, a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Murr C, et al. Neopterin as a Marker for Immune System Activation. Current Drug Metabolism [01 Apr 2002, 3(2):175-187].

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 697.7ºC at 760mmHg
Melting Point >232ºC (dec.)
Molecular Formula C9H11N5O4
Molecular Weight 253.215
Flash Point 375.7ºC
Exact Mass 253.081100
PSA 158.50000
LogP -4.57
Index of Refraction 1.860

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

~62%

D-erythro-Neopterin Structure

D-erythro-Neopterin

CAS#:2009-64-5

Literature: Sugimoto; Matsuura; Nagatsu Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 8 p. 2344 - 2347

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D-erythro-Neopterin Structure

D-erythro-Neopterin

CAS#:2009-64-5

Literature: Journal of the American Chemical Society, , vol. 80, p. 2018

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D-erythro-Neopterin Structure

D-erythro-Neopterin

CAS#:2009-64-5

Literature: Bulletin of the Chemical Society of Japan, , vol. 53, # 8 p. 2344 - 2347

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles37

More Articles
Increased serum levels of quinolinic acid indicate enhanced severity of hepatic dysfunction in patients with liver cirrhosis.

Hum. Immunol. 74(1) , 60-6, (2013)

The Model for End-Stage Liver Disease (MELD) score is a tool for assessment of the degree of hepatic insufficiency/failure. Quinolinic acid (QuinA) is a tryptophan metabolite produced by activated mac...

A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.

Clin. Exp. Immunol. 173(1) , 121-30, (2013)

Circulating neopterin and kynurenine/tryptophan ratio (KTR) increase during inflammation and serve as markers of cellular immune activation, but data are sparse on other determinants of these markers ...

Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study.

Clin. Exp. Immunol. 176(3) , 452-60, (2014)

The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamin...

 Synonyms

2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(1H)-pteridinone
Crithidia Factor
2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]pteridin-4(3H)-one
1-(2-amino-4-hydroxy-pteridin-6-yl)propane-1,2,3-triol
EINECS 217-924-7
2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]pteridin-4(8H)-one
D-Neopterin
2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(1H)-ptéridinone
MFCD00042801
4(8H)-pteridinone, 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-
6-(1',2',3'-Trihydroxy)pterin
D(+)-Neopterin 10MG
D(+)-6-(ERYTHRO-1,2,3-TRIHYDROXYPROPYL)PTERIN
D-neopterine
Gavestinel
D-(+)-Neopterin
D-(PLUS)-NEOPTERINE
2-amino-6-((1S,2R)-1,2,3-trihydroxy-propyl)-3H-pteridin-4-one
(+)-NEOPTERIN
D-erythro-neopterin
4(3H)-Pteridinone, 2-amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-
2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(1H)-pteridinon
Neopterin
D(+)-Neopterin
2-amino-6-(1,2,3-trihydroxy-propyl)-3H-pteridin-4-one
2-AMino-6-[(1S,2R)-1,2,3-trihydroxypropyl]