Methylamino-PEG5-azide

Modify Date: 2024-02-21 19:28:53

Methylamino-PEG5-azide Structure
Methylamino-PEG5-azide structure
Common Name Methylamino-PEG5-azide
CAS Number 2055046-24-5 Molecular Weight 320.39
Density N/A Boiling Point N/A
Molecular Formula C13H28N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Methylamino-PEG5-azide


Methylamino-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methylamino-PEG5-azide

 Methylamino-PEG5-azide Biological Activity

Description Methylamino-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H28N4O5
Molecular Weight 320.39